Associate Director/Director, Computational Biologist

July 24

🏢 In-office - San Francisco

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BridgeBio

Hope Through Rigorous Science

201 - 500

Description

• The Computational Genetics team is seeking a full-time Computational Biologist who will guide strategic initiatives and directly contribute to identifying and extracting biological insights from high dimensional multi-omics data. • The team provides data-driven insights to make critical decisions for pursuing new opportunities and advancing internal development projects across early discovery and clinical stage programs. The successful candidate will be working alongside human geneticists, data scientists as well as experimental biologists for the ultimate goal of developing drugs for genetic diseases with high unmet need. • The role involves leveraging methods from multiple disciplines including computational genetics, statistical inference, and machine learning.

Requirements

• PhD in Bioinformatics, Computational Biology, Functional Genomics or related discipline with 5+ years of industry experience applying multi-omics data analyses in the human context • Has direct experience with databases that house multi-omics datasets such as UK Biobank, Human Cell Atlas, Human Protein Atlas, GEO, Expression Atlas, DepMap, etc. • Understands the limitations of high-throughput data with direct experience in quality control across multiple types of omics data, as well as how to assess quality of summarized results • Expert level of proficiency in quantitative analyses, including mathematics, statistics and computation • Able to demonstrate great written and verbal communication skills in conveying analysis results to both experts and non-experts in the field • Extensive experience with Python focusing on data analysis and familiarity with git version control; hands on experience in developing data processing pipelines and or developing stand-alone libraries is a plus • Understands AWS infrastructure, including EC2, S3 and knowledge of relational databases (SQL, Postgres, etc…); experience in extracting information from such databases • Proven track record of peer-reviewed publications in computational biology

Benefits

• Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts • A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak • An unyielding commitment to always putting patients first. Learn more about how we do this here • A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science • A place where you own the vision – both for your program and your own career path • A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game • Access to learning and development resources to help you get in the best professional shape of your life • Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs) • Flexible PTO • Rapid career advancement for strong performers • Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time • Partnerships with leading institutions • Commitment to Diversity, Equity & Inclusion

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