Principal Scientist/Associate Director, Medicinal Chemistry

July 24

🏢 In-office - San Francisco

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Logo of Cytokinetics

Cytokinetics

Empowering Muscle Empowering Lives

Heart Failure • Amyotrophic Lateral Sclerosis • Hypertrophic Cardiomyopathy

201 - 500

💰 $450M Post-IPO Debt on 2022-06

Description

• Lead research project teams with scientific excellence and urgency to enable progression of research compounds into the clinic. • Manage the development of scalable routes for potential development compounds that can be easily transitioned to a process chemistry group. • Partner with research leaders to develop a robust small molecule portfolio that is aligned with Cytokinetics strategic vision. • Collaborate closely with all functional area leaders in research to ensure efficient workflows and to maintain a diverse and inclusive work environment • Mentor and support the career development of colleagues within the medicinal chemistry group • In collaboration with EH&S, oversee and enforce safe working practices within the medicinal chemistry lab. • External communication of Cytokinetics research through publications and presentations

Requirements

• Doctorate level degree in relevant area of chemistry, or equivalent industrial experience with 10+ years of relevant experience developing small molecule drugs within the pharmaceutical industry • Prior experience in Targeted Protein Degradation is strongly desired. • High level of synthetic chemistry expertise and working knowledge of the important considerations for process development and manufacturing • Strong record of high impact contributions to research projects that enable progression into the clinic. • Minimum 5+ experience managing and developing scientists. • Good understanding of the concepts that drive decision making within all key research and development technical areas that are responsible for drug discovery and development • Experience collaborating with and leading teams of internal/CRO staff scientists to meet project goals. • Strong record of peer-reviewed scientific publications and presentation. • Highly organized with excellent verbal and written communication skills

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