Synthetic lethality precision medicine oncology company pursuing– an emerging class of precision medicine targets.
Synthetic Lethality and Precision Medicine
July 25
🏢 In-office - San Francisco
Synthetic lethality precision medicine oncology company pursuing– an emerging class of precision medicine targets.
Synthetic Lethality and Precision Medicine
• Lead the analytical chemistry efforts in facilitating internal drug discovery by managing and executing compound purification (including chiral separations), structural elucidation, biophysical property determinations (such as solubility, logD, and pKa determinations), and stability studies • Manage Discovery Analytical group to achieve high productivity with high quality and high scientific rigor • Troubleshoot methods and provide technical guidance across discovery programs • Manage installation and maintenance of lab analytical equipment. • Train and supervise research associate and scientists to ensure proper execution of analytical experiments • Perform vendor review and selection and provide oversight of all external analytical work • Ensure analytical method qualification/validation/technical-transfer documentation (test protocols, methods, and reports) are relevant, accurate, and complete • Stay aware of newly emerging techniques and technologies and bring new capabilities online as necessary • Proactively communicate with and work closely with other functions to align analytical strategy to achieve goals • Hire high-caliber analytical chemists to build and grow a world-class analytical department • Craft and manage budgets
• Ph.D. in analytical chemistry or related discipline with minimum of (10) years of drug discovery/development experiences and demonstrated ability in leading cross-functional groups • Strong subject matter expertise in small molecule purification, structural elucidation, multidisciplinary chemical analysis, analytical method development/validation, and CRO management • Exceptional problem-solving skills and ability to quickly adapt and shift focus as needed • Excellent interpersonal and communication skills for internal and external collaborations • Demonstrated ability in strategic plans and prioritization of a portfolio of projects • Ability to multi-task in a fast-paced dynamic environment while demonstrating a calm and positive attitude and a superior work ethic • Demonstrated strong record of managing direct reports and/or teams successfully • Desire and ability to mentor junior level associates and scientists, including direct reports or supporting team members
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