Scientist, Antibody Engineering

May 23

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Twist Bioscience

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Synthetic DNA for Health & Sustainability

Synthetic Biology • DNA • Biotechnology • Drug Discovery • Gene Synthesis

501 - 1000

Description

• Lead the generation of therapeutic and reagent antibodies by phage, ribosome, or yeast display technologies to meet design criteria set by external and internal stakeholders. • Lead biopharma programs to maintain project timelines and report progress regularly to the project team and external stakeholders. • Contribute to display library design and construction using public and in-house generated data. • Perform library construction, selection, and screening to identify desirable antibodies against diverse targets, including cell expression targets. • Apply Ab engineering tools and expertise to design and execute antibody humanization and optimization. • Have solid knowledge of antibody phage display or other related display technology. • Perform high throughput primary binding assays with automation. • Work collaboratively under aggressive timelines. • 80% of the time will be spent on bench work.

Requirements

• PhD or equivalent in Biochemistry, Molecular Biology, Protein Engineering or related field; MS / MA with 2-5 years of industry experience. • Extensive skills in molecular biology and antibody engineering methods/best practices and applications. • Experience with at least one of the antibody display technologies, such as phage, ribosome or yeast required. • Extensive use of scientific databases and applications for data management and data analysis, including, but not limited to, DNA sequence analysis of antibody genes. • Experience in antibody or protein characterization. • Hands-on expertise with automated platforms. • Excellent written and verbal communication skills are required.

Benefits

• In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. • Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above.