Research Associate/Senior Research Associate, Nucleic Acid Analytics
3 days ago
🏢 In-office - San Francisco
Description
• SonoThera is seeking a Research Associate/Senior Research Associate to support gene therapy development. • Conduct RNA and DNA sample preparation for analysis. • Characterize gene therapy vector delivery efficiency in preclinical models. • Develop and optimize ddPCR and NGS protocols for analytics including single cell analysis.
Requirements
• Bachelor's or Master’s degree in the biological sciences (e.g. Genetics, Biochemistry, Molecular and Cellular Biology, Physiology, or related field) with 2-5 years of relevant postgraduate research experience in an industry setting. • Creativity and the ability to work within an interdisciplinary team to achieve technical and corporate milestones. • Strong verbal and written communication, critical thinking, and problem-solving skills. • Proven track record of running CN/DG analysis (DNA extraction from animal tissues, ddPCR) and RNA expression analysis (RNA extraction from animal tissues, RT-ddPCR). • Extensive experience developing and optimizing new ddPCR assays, including primer/probe design and testing. • Previous experience using high-throughput methods for DNA/RNA extraction and ddPCR setup including robotic liquid handlers (i.e. Agilent Bravo) and plate-based extractions (i.e. QIAGEN 96 kits). • Expertise in sample and library preparation for bulk-tissue RNA-seq, scRNA-seq, snRNA-seq. • Experience in library sequencing using Illumina platforms (i.e. NextSeq2000). • Experience in data analysis (i.e. GraphPad Prism), as well as slide preparation and presentation. • Ideal candidate will have familiarity with ELNs (i.e. Benchling), qPCR, Olink-based proteomics, MSD, protein isolation, Western blot, histology analysis. • Strong record-keeping and organizational skills.
Benefits
• Equity and ownership in a fast-growing company. • Access to a 24-hour gym • Comprehensive medical, dental, and vision • Commuting stipend based on your geographical location • 401(k) Match: SonoThera offers a dollar-for-dollar match • All full-time employees are eligible for our flexible time off policy
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