Senior Scientist I/II, Antibody Engineering
August 16
🏢 In-office - San Francisco
Description
• Utilize phage display methodologies to discover novel antibodies or engineer existing antibodies to improve their functional activities. • Use state-of-the-art phage display methods and high throughput ELISA-based and FACS-based screening. • Use BLI (Gator or Octet) or SPR (Biacore) based platforms to perform kinetic characterizations of antibody fragments or monoclonal antibodies. • Perform high-throughput sequence analysis of potential candidates using sequence analysis software (e.g. Geneious Prime and AbYsis) • Regularly communicate results to company supervisors, present updates during internal or joint team meetings with other companies. • Multi-task, plan, execute, and deliver on projects which may be run in parallel. • Identify and promptly troubleshoot technical issues. • Maintain detailed lab records and perform electronic data management. • Participate in reagent and lab supplies procurement and perform and/or oversee routine maintenance on instruments and equipment.
Requirements
• Ph.D. with 4+ years of experience in molecular biology, biochemistry, chemical engineering or related field is required • Phage display experience is required • Extensive experience in ELISA based screening is required • Deep knowledge of molecular biology techniques and PCR is highly desired. • Knowledge of DNA sequence analysis software is required • Knowledge of FACS screening and analysis is desired. • Experience with SPR/BLI is desired but not required. • Excellent attention to detail, record keeping, and communication skills. • Strong ability to work independently and manage work with minimal supervision.
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